1952 ⟶ Frederick Sanger: Protein Sequence Determination

Frederick Sanger: demonstrated that proteins are sequences o...
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Year
1907
1951
1952
1953
1977

🔬 Fischer Synthesizes Peptide Amino Acid Chains

Hermann Emil Fischer artificially synthesized peptide amino acid chains and thereby shows that amino acids in proteins are connected by amino group-acid group bonds.⟶
Fischer Synthesizes Peptide Amino Acid Chains (1907)
BiochemistryOrganic ChemistryHermann Emil FischerProteinsAmino AcidsPeptidesSynthesisEarly 20th Century
GermanyGermany

🧬 Chromatographic Analysis of Insulin's Amino Acid Sequence

Fred Sanger, Hans Tuppy completed their chromatographic analysis of the insulin amino acid sequence.⟶
Chromatographic Analysis of Insulin's Amino Acid Sequence (1951)
BiologyBiochemistryProtein SequencingInsulinFred SangerChromatographyAmino AcidsMolecular Biology
United KingdomUnited Kingdom

🔬 Deduction of Protein Secondary Structure

Linus Pauling uses X-ray crystallography to deduce the secondary structure of proteins.⟶
Deduction of Protein Secondary Structure (1951)
BiologyBiophysicsProtein StructureX-ray CrystallographyLinus PaulingSecondary StructureMolecular BiologyStructural Biology
United StatesUnited States

🧪 Frederick Sanger: Protein Sequence Determination

Frederick Sanger: demonstrated that proteins are sequences of amino acids⟶
Frederick Sanger: Protein Sequence Determination (1952)
BiochemistryProtein StructureAmino AcidsMolecular BiologyCambridgeSanger1950sAnalytical ChemistryOrganic ChemistryScientific Method
United KingdomUnited Kingdom

⚡ Stanley Miller: Amino Acid Formation from Simulated Lightning

Stanley Miller showed that amino acids can be formed when simulated lightning is passed through vessels containing water, methane, ammonia, and hydrogen⟶
Stanley Miller: Amino Acid Formation from Simulated Lightning (1953)
Origin of LifeAmino AcidsPrebiotic ChemistryMillerUreyOrganic ChemistryAstrobiology1950sExperimentBiogenesis
United StatesUnited States

🧪 Frederick Sanger Sequences First DNA Genome of an Organism

Frederick Sanger sequences the first DNA genome of an organism using Sanger sequencing⟶
Frederick Sanger Sequences First DNA Genome of an Organism (1977)
Molecular BiologyDNA SequencingGenetics1970sFrederick SangerSanger SequencingGenomePhiX174
United KingdomUnited Kingdom