1951Chromatographic Analysis of Insulin's Amino Acid Sequence

Fred Sanger, Hans Tuppy completed their chromatographic anal...
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1907
1951
1952
1968
1969

🔬 Fischer Synthesizes Peptide Amino Acid Chains

Hermann Emil Fischer artificially synthesized peptide amino acid chains and thereby shows that amino acids in proteins are connected by amino group-acid group bonds.
Fischer Synthesizes Peptide Amino Acid Chains (1907)
BiochemistryOrganic ChemistryHermann Emil FischerProteinsAmino AcidsPeptidesSynthesisEarly 20th Century
GermanyGermany

🧬 Chromatographic Analysis of Insulin's Amino Acid Sequence

Fred Sanger, Hans Tuppy completed their chromatographic analysis of the insulin amino acid sequence.
Chromatographic Analysis of Insulin's Amino Acid Sequence (1951)
BiologyBiochemistryProtein SequencingInsulinFred SangerChromatographyAmino AcidsMolecular Biology
United KingdomUnited Kingdom

🔬 Deduction of Protein Secondary Structure

Linus Pauling uses X-ray crystallography to deduce the secondary structure of proteins.
Deduction of Protein Secondary Structure (1951)
BiologyBiophysicsProtein StructureX-ray CrystallographyLinus PaulingSecondary StructureMolecular BiologyStructural Biology
United StatesUnited States

🧪 Frederick Sanger: Protein Sequence Determination

Frederick Sanger: demonstrated that proteins are sequences of amino acids
Frederick Sanger: Protein Sequence Determination (1952)
BiochemistryProtein StructureAmino AcidsMolecular BiologyCambridgeSanger1950sAnalytical ChemistryOrganic ChemistryScientific Method
United KingdomUnited Kingdom

🔬 Fred Sanger Deciphers RNA Sequence Using Radioactive Phosphorus

Fred Sanger used radioactive phosphorus as a tracer to chromatographically decipher a 120 base long RNA sequence.
Fred Sanger Deciphers RNA Sequence Using Radioactive Phosphorus (1968)
Molecular BiologyRNA SequencingBiochemistryChromatographyRadioactive IsotopesSanger SequencingFred Sanger
United KingdomUnited Kingdom

🧬 Dorothy Crowfoot Hodgkin Deciphers Insulin's 3D Structure

Dorothy Crowfoot Hodgkin deciphered the three-dimensional structure of insulin.
Dorothy Crowfoot Hodgkin Deciphers Insulin's 3D Structure (1969)
BiochemistryStructural BiologyX-ray CrystallographyInsulinDorothy Crowfoot HodgkinProtein Structure
United KingdomUnited Kingdom