1953Watson and Crick Propose DNA Structure and Molecular Biology

James D. Watson and Francis Crick propose the structure of D...
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Year
1952
1953
1955

🧪 Hershey-Chase Experiment: DNA as Genetic Material

Alfred Hershey and Martha Chase showed that DNA is the genetic material in bacteriophage viruses.
Hershey-Chase Experiment: DNA as Genetic Material (1952)
BiologyGeneticsMolecular BiologyDNAAlfred HersheyMartha ChaseBacteriophagesGenetic Material
United StatesUnited States

🧬 Rosalind Franklin's X-ray Diffraction of DNA

Rosalind Franklin concluded that DNA is a double helix with a diameter of 2 nm and the sugar-phosphate backbones on the outside of the helix, based on x ray diffraction studies. She suspected the two sugar-phosphate backbones have a peculiar relationship to each other.
Rosalind Franklin's X-ray Diffraction of DNA (1952)
BiologyMolecular BiologyDNA StructureX-ray DiffractionRosalind FranklinDouble HelixStructural BiologyChargaff's Rules
United KingdomUnited Kingdom

🧬 Watson and Crick Propose DNA Structure and Molecular Biology

James D. Watson and Francis Crick propose the structure of DNA, opening the door to the field of molecular biology.
Watson and Crick Propose DNA Structure and Molecular Biology (1953)
Molecular BiologyDNAWatsonCrickDouble HelixGeneticsScientific RevolutionCambridge1950sScientific Discovery
United KingdomUnited Kingdom

🧬 Watson and Crick Publish DNA Double Helix Structure

After examining Franklin's unpublished data, James D. Watson and Francis Crick published a double-helix structure for DNA, with one sugar-phosphate backbone running in the opposite direction to the other. They further suggested a mechanism by which the molecule can replicate itself and serve to transmit genetic information. Their paper, combined with the Hershey-Chase experiment and Chargaff's data on nucleotides, finally persuaded biologists that DNA is the genetic material, not protein.
Watson and Crick Publish DNA Double Helix Structure (1953)
Molecular BiologyDNAGeneticsWatsonCrickDouble HelixChargaffHershey-Chase ExperimentScientific Revolution1950s
United KingdomUnited KingdomUnited StatesUnited States

⚛️ Arthur Kornberg: DNA Polymerase Discovery

Arthur Kornberg: DNA Polymerase Discovery (1955)
BiochemistryEnzymesDNA PolymeraseKornbergDNA ReplicationMolecular Biology1950sScientific ResearchNucleic AcidsGenetics
United StatesUnited States