1952Rosalind Franklin's X-ray Diffraction of DNA

Rosalind Franklin concluded that DNA is a double helix with ...
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Year
1951
1952
1953

🔬 Deduction of Protein Secondary Structure

Linus Pauling uses X-ray crystallography to deduce the secondary structure of proteins.
Deduction of Protein Secondary Structure (1951)
BiologyBiophysicsProtein StructureX-ray CrystallographyLinus PaulingSecondary StructureMolecular BiologyStructural Biology
United StatesUnited States

🧬 Rosalind Franklin's X-ray Diffraction of DNA

Rosalind Franklin concluded that DNA is a double helix with a diameter of 2 nm and the sugar-phosphate backbones on the outside of the helix, based on x ray diffraction studies. She suspected the two sugar-phosphate backbones have a peculiar relationship to each other.
Rosalind Franklin's X-ray Diffraction of DNA (1952)
BiologyMolecular BiologyDNA StructureX-ray DiffractionRosalind FranklinDouble HelixStructural BiologyChargaff's Rules
United KingdomUnited Kingdom

🧪 Hershey-Chase Experiment: DNA as Genetic Material

Alfred Hershey and Martha Chase showed that DNA is the genetic material in bacteriophage viruses.
Hershey-Chase Experiment: DNA as Genetic Material (1952)
BiologyGeneticsMolecular BiologyDNAAlfred HersheyMartha ChaseBacteriophagesGenetic Material
United StatesUnited States

🧬 Watson and Crick Publish DNA Double Helix Structure

After examining Franklin's unpublished data, James D. Watson and Francis Crick published a double-helix structure for DNA, with one sugar-phosphate backbone running in the opposite direction to the other. They further suggested a mechanism by which the molecule can replicate itself and serve to transmit genetic information. Their paper, combined with the Hershey-Chase experiment and Chargaff's data on nucleotides, finally persuaded biologists that DNA is the genetic material, not protein.
Watson and Crick Publish DNA Double Helix Structure (1953)
Molecular BiologyDNAGeneticsWatsonCrickDouble HelixChargaffHershey-Chase ExperimentScientific Revolution1950s
United KingdomUnited KingdomUnited StatesUnited States