1929Linus Pauling Publishes Pauling's Rules for X-ray Crystallography

Linus Pauling publishes Pauling's rules, which are key princ...
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1928
1929
1937
1939
1951
1958

⚛️ Diels-Alder Reaction: Cycloaddition for Ring Molecule Formation

Otto Diels and Kurt Alder discovered the Diels-Alder cycloaddition reaction for forming ring molecules.
Diels-Alder Reaction: Cycloaddition for Ring Molecule Formation (1928)
ChemistryOrganic ChemistryChemical ReactionCycloadditionDiels-Alder ReactionSynthetic ChemistryMolecular Structure20th Century
GermanyGermany

🔬 Linus Pauling Publishes Pauling's Rules for X-ray Crystallography

Linus Pauling publishes Pauling's rules, which are key principles for the use of X-ray crystallography to deduce molecular structure.
Linus Pauling Publishes Pauling's Rules for X-ray Crystallography (1929)
ChemistryX-ray CrystallographyMolecular StructureLinus PaulingPauling's RulesCrystallographyStructural Chemistry20th Century
United StatesUnited States

🧬 Dorothy Crowfoot Hodgkin discovers the three-dimensional structure of cholesterol

Dorothy Crowfoot Hodgkin discovered the three-dimensional structure of cholesterol.
Dorothy Crowfoot Hodgkin discovers the three-dimensional structure of cholesterol (1937)
BiochemistryX-ray CrystallographyDorothy Crowfoot HodgkinCholesterolOrganic ChemistryStructure Determination20th CenturyMolecular Structure
United KingdomUnited Kingdom

🧪 Linus Pauling Publishes The Nature of the Chemical Bond

Linus Pauling publishes The Nature of the Chemical Bond, a compilation of a decades worth of work on chemical bonding. It is one of the most important modern chemical texts. It explains hybridization theory, covalent bonding and ionic bonding as explained through electronegativity, and resonance as a means to explain, among other things, the structure of benzene.
Linus Pauling Publishes The Nature of the Chemical Bond (1939)
ChemistryChemical BondingLinus PaulingMolecular StructureCovalent BondingIonic BondingHybridizationElectronegativityResonance1930s
United StatesUnited States

🔬 Deduction of Protein Secondary Structure

Linus Pauling uses X-ray crystallography to deduce the secondary structure of proteins.
Deduction of Protein Secondary Structure (1951)
BiologyBiophysicsProtein StructureX-ray CrystallographyLinus PaulingSecondary StructureMolecular BiologyStructural Biology
United StatesUnited States

🔬 Protein Structure Elucidated via X-ray Crystallography

Max Perutz and John Kendrew use X-ray crystallography to elucidate a protein structure, specifically sperm whale myoglobin.
Protein Structure Elucidated via X-ray Crystallography (1958)
X-ray CrystallographyProtein StructureMyoglobinMolecular BiologyMax PerutzJohn Kendrew
United KingdomUnited Kingdom