1961First Codon of the Genetic Code Cracked

J. Heinrich Matthaei cracked the first codon of the genetic ...
Timelines Logo
Year
1943
1952
1960
1961
1966

🧬 Oswald Avery proves DNA is genetic material

Oswald Avery proves that DNA is the genetic material of the chromosome
Oswald Avery proves DNA is genetic material (1943)
GeneticsDNAMolecular BiologyAveryChromosomeHeredityScientific Breakthrough20th Century Science
USAUSA

🧪 Hershey-Chase Experiment: DNA as Genetic Material

Alfred Hershey and Martha Chase showed that DNA is the genetic material in bacteriophage viruses.
Hershey-Chase Experiment: DNA as Genetic Material (1952)
BiologyGeneticsMolecular BiologyDNAAlfred HersheyMartha ChaseBacteriophagesGenetic Material
United StatesUnited States

🦠 Discovery of Bacterial RNA Polymerase

Four separate researchers (S. Weiss, J. Hurwitz, Audrey Stevens Niyogi and J. Bonner) discovered bacterial RNA polymerase, which polymerizes nucleotides under the direction of DNA.
Discovery of Bacterial RNA Polymerase (1960)
RNA PolymeraseMolecular BiologyGeneticsTranscriptionBacteriaS. WeissJ. HurwitzAudrey Stevens NiyogiJ. Bonner
United StatesUnited States

🅰️ First Codon of the Genetic Code Cracked

J. Heinrich Matthaei cracked the first codon of the genetic code (the codon for the amino acid phenylalanine) using Grunberg-Manago's 1955 enzyme system for making polynucleotides.
First Codon of the Genetic Code Cracked (1961)
Genetic CodeCodonGeneticsMolecular BiologyJ. Heinrich MatthaeiPolynucleotides
GermanyGermany

🧬 Genetic Code Fully Cracked

Genetic code fully cracked through trial-and-error experimental work.
GeneticsMolecular BiologyGenetic CodeProtein SynthesisTrial-and-error1960sDNACentral Dogma
United KingdomUnited KingdomUnited StatesUnited States