1966Dendral Program Interprets Mass Spectra

Dendral program (Edward Feigenbaum, Joshua Lederberg, Bruce ...
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1965
1966
1968
1975
1979

🧪 Dendral: Expert System for Molecular Structure

Edward Feigenbaum initiated Dendral, a ten-year effort to develop software to deduce the molecular structure of organic compounds using scientific instrument data. It was the first Expert system.
Dendral: Expert System for Molecular Structure (1965)
Expert SystemsKnowledge-Based SystemsStanford UniversityFeigenbaumMolecular StructureScientific ReasoningEarly AIDendral
United StatesUnited States

🔬 Dendral Program Interprets Mass Spectra

Dendral program (Edward Feigenbaum, Joshua Lederberg, Bruce Buchanan, Georgia Sutherland at Stanford University) demonstrated to interpret mass spectra on organic chemical compounds. First successful knowledge-based program for scientific reasoning.
Dendral Program Interprets Mass Spectra (1966)
Expert SystemsKnowledge-Based SystemsStanford UniversityScientific ReasoningChemistryFeigenbaumDendral
United StatesUnited States

➕ Macsyma: Symbolic Reasoning for Integration

Joel Moses (PhD work at MIT) demonstrated the power of symbolic reasoning for integration problems in the Macsyma program. First successful knowledge-based program in Mathematics.
Macsyma: Symbolic Reasoning for Integration (1968)
Symbolic ReasoningMathematicsKnowledge-Based SystemsMITMacsymaMoses
United StatesUnited States

🧪 Meta-Dendral Produces New Chemistry Results

The Meta-Dendral learning program produced new results in Chemistry (some rules of Mass spectrometry) the first scientific discoveries by a computer to be published in a refereed journal.
Meta-Dendral Produces New Chemistry Results (1975)
Expert SystemsChemistryScientific DiscoveryMachine LearningRule-based SystemsMeta-DendralStanford University
USAUSA

🗣️ EMYCIN Program Development

Bill VanMelle's PhD dissertation at Stanford demonstrated the generality of MYCIN's representation of knowledge and style of reasoning in his EMYCIN program, the model for many commercial expert system "shells".
EMYCIN Program Development (1979)
Expert SystemsEMYCINKnowledge RepresentationReasoningMYCINBill VanMelleStanford University
USAUSA