1948Chargaff's rules about DNA base pairing

Erwin Chargaff showed that in DNA the number of guanine unit...
Timelines Logo
Year
1943
1944
1948
1952
1953

🧬 Oswald Avery proves DNA is genetic material

Oswald Avery proves that DNA is the genetic material of the chromosome
Oswald Avery proves DNA is genetic material (1943)
GeneticsDNAMolecular BiologyAveryChromosomeHeredityScientific Breakthrough20th Century Science
USAUSA

🧪 Oswald Avery demonstrates DNA's role in carrying hereditary information

Oswald Avery shows that DNA carried the hereditary information in pneumococcus bacteria.
Oswald Avery demonstrates DNA's role in carrying hereditary information (1944)
GeneticsDNAMolecular BiologyAveryHeredityPneumococcusScientific Breakthrough20th Century Science
USAUSA

⚖️ Chargaff's rules about DNA base pairing

Erwin Chargaff showed that in DNA the number of guanine units equals the number of cytosine units and the number of adenine units equals the number of thymine units.
Chargaff's rules about DNA base pairing (1948)
GeneticsDNAChargaffBase PairingMolecular BiologyHeredityDNA Structure20th Century Science
AustriaAustria

🧪 Hershey-Chase Experiment: DNA as Genetic Material

Alfred Hershey and Martha Chase showed that DNA is the genetic material in bacteriophage viruses.
Hershey-Chase Experiment: DNA as Genetic Material (1952)
BiologyGeneticsMolecular BiologyDNAAlfred HersheyMartha ChaseBacteriophagesGenetic Material
United StatesUnited States

🧬 Watson and Crick Publish DNA Double Helix Structure

After examining Franklin's unpublished data, James D. Watson and Francis Crick published a double-helix structure for DNA, with one sugar-phosphate backbone running in the opposite direction to the other. They further suggested a mechanism by which the molecule can replicate itself and serve to transmit genetic information. Their paper, combined with the Hershey-Chase experiment and Chargaff's data on nucleotides, finally persuaded biologists that DNA is the genetic material, not protein.
Watson and Crick Publish DNA Double Helix Structure (1953)
Molecular BiologyDNAGeneticsWatsonCrickDouble HelixChargaffHershey-Chase ExperimentScientific Revolution1950s
United KingdomUnited KingdomUnited StatesUnited States

🧬 Watson and Crick Propose DNA Structure and Molecular Biology

James D. Watson and Francis Crick propose the structure of DNA, opening the door to the field of molecular biology.
Watson and Crick Propose DNA Structure and Molecular Biology (1953)
Molecular BiologyDNAWatsonCrickDouble HelixGeneticsScientific RevolutionCambridge1950sScientific Discovery
United KingdomUnited Kingdom