1994 ⟶ Total Synthesis of Taxol Achieved

First total synthesis of Taxol by Robert A. Holton and his ...
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Year
1828
1847
1951
1960
1972
1994

🧪 Friedrich Woehler Synthesizes Urea

Friedrich Woehler synthesized urea; first synthesis of an organic compound from inorganic starting materials.⟶
Friedrich Woehler Synthesizes Urea (1828)
ChemistryOrganic chemistryUreaChemical synthesisVitalism19th centuryWoehler
GermanyGermany

🧪 Acetic Acid Synthesis Disproves Vitalism

Hermann Kolbe obtains acetic acid from completely inorganic sources, further disproving vitalism.⟶
Acetic Acid Synthesis Disproves Vitalism (1847)
ChemistryOrganic ChemistryVitalismHermann KolbeSynthesis19th CenturyChemical Synthesis
GermanyGermany

🧪 Synthesis of Cholesterol and Cortisone

The research group of Robert Robinson with John Cornforth (Oxford University) publishes their synthesis of cholesterol, while Robert Woodward (Harvard University) publishes his synthesis of cortisone.⟶
Synthesis of Cholesterol and Cortisone (1951)
ChemistryOrganic ChemistrySynthesisCholesterolCortisoneRobert RobinsonRobert WoodwardDrug DiscoverySteroid Chemistry
United KingdomUnited KingdomUnited StatesUnited States

🌿 Chlorophyll Synthesis

Robert Woodward synthesized chlorophyll.⟶
Chlorophyll Synthesis (1960)
Organic ChemistryChlorophyllPhotosynthesisRobert WoodwardChemical Synthesis
United StatesUnited States

💊 Synthesis of Vitamin B12

Albert Eschenmoser and Robert Woodward synthesized vitamin B12.⟶
Synthesis of Vitamin B12 (1972)
ChemistryOrganic ChemistryVitamin B12SynthesisAlbert EschenmoserRobert WoodwardComplex Molecule1970s
SwitzerlandSwitzerland

🧪 Total Synthesis of Taxol Achieved

First total synthesis of Taxol by Robert A. Holton and his group.⟶
Total Synthesis of Taxol Achieved (1994)
ChemistryOrganic ChemistryTotal SynthesisTaxolDrug DiscoveryRobert A. Holton
USAUSA