1824Sperm Discovered to be Agents of Fertilization

J. L. Prevost and J. B. Dumas showed that the sperm in semen...
Timelines Logo
Year
1768
1824
1826
1843
1876

🔬 Lazzaro Spallanzani Disproves Spontaneous Generation and Studies Reproduction

Lazzaro Spallanzani again disproved spontaneous generation by showing that no organisms grow in a rich broth if it is first heated (to kill any organisms) and allowed to cool in a stoppered flask. He also showed that fertilization in mammals requires an egg and semen.
Lazzaro Spallanzani Disproves Spontaneous Generation and Studies Reproduction (1768)
BiologySpontaneous GenerationLazzaro SpallanzaniGerm TheoryReproduction18th CenturyFertilization
ItalyItaly

🥚 Sperm Discovered to be Agents of Fertilization

J. L. Prevost and J. B. Dumas showed that the sperm in semen were not parasites, as previously thought, but, instead, the agents of fertilization.
BiologyReproductionFertilizationSpermJ. L. PrevostJ. B. Dumas19th Century BiologyEmbryologySexuality
FranceFrance

🥚 Karl von Baer Discovers Mammalian Eggs in Ovaries

Karl von Baer showed that the eggs of mammals are in the ovaries, ending a 200-year search for the mammalian egg.
Karl von Baer Discovers Mammalian Eggs in Ovaries (1826)
BiologyEmbryologyMammalian eggReproduction19th centuryOvariesZoology
EstoniaEstonia

🥚 Fusion of Sperm and Egg Observed in Rabbits

Martin Barry reported the fusion of a sperm and an egg for rabbits in a 1-page paper in the Philosophical Transactions of the Royal Society of London.
BiologyReproductionFertilizationMartin BarryEmbryology19th CenturyCell Biology
United KingdomUnited Kingdom

🥚 Hertwig and Fol Describe Sperm Entry and Egg Fusion

Oskar Hertwig and Hermann Fol independently described (in sea urchin eggs) the entry of sperm into the egg and the subsequent fusion of the egg and sperm nuclei to form a single new nucleus.
Hertwig and Fol Describe Sperm Entry and Egg Fusion (1876)
FertilizationCell BiologyReproductionHertwigFolEmbryology19th Century Biology
GermanyGermany