1648 ⟶ Publication of van Helmont's *Ortus medicinae* and Early Conservation of Mass
Posthumous publication of the book Ortus medicinae by Jan Ba...Year
1597
1648
1661
1782
1840
🧪 Libavius Publishes *Alchemia*
Andreas Libavius publishes Alchemia, a prototype chemistry textbook.⟶

ChemistryLibaviusTextbookAlchemyScientific LiteratureEarly ChemistryRenaissance

🧪 Publication of van Helmont's *Ortus medicinae* and Early Conservation of Mass
Posthumous publication of the book Ortus medicinae by Jan Baptist van Helmont, which is cited by some as a major transitional work between alchemy and chemistry, and as an important influence on Robert Boyle. The book contains the results of numerous experiments and establishes an early version of the law of conservation of mass.⟶

ChemistryAlchemyJan Baptist van HelmontConservation of MassChemical Reactions17th CenturyEarly ChemistryRobert BoyleExperimentation

⚛️ Robert Boyle Publishes *The Sceptical Chymist*
Robert Boyle publishes The Sceptical Chymist, a treatise on the distinction between chemistry and alchemy. It contains some of the earliest modern ideas of atoms, molecules, and chemical reaction, and marks the beginning of the history of modern chemistry.⟶

ChemistryRobert BoyleAlchemyAtomsMoleculesChemical Reaction17th CenturyScientific RevolutionModern Chemistry
⚖️ Antoine Lavoisier Proposes Conservation of Mass

ChemistryLaw of Conservation of MassLavoisierStoichiometryQuantitative Analysis18th CenturyScientific RevolutionChemical Reactions

🧪 Hess's Law: Conservation of Energy in Chemical Processes
Germain Hess proposes Hess's law, an early statement of the law of conservation of energy, which establishes that energy changes in a chemical process depend only on the states of the starting and product materials and not on the specific pathway taken between the two states.⟶

ChemistryThermodynamicsEnergyConservation of EnergyHess's LawGermain Hess19th CenturyChemical Reactions
